Pediatric Surgery, Orthopedics and Anesthesiology

 
 

Research

“Diagnostic and medico-surgical management of malformative urinary pathologies in newborns and babies under 3 years”. Pediatric Surgery – 14.00.35, Scientific Specialized Consilium DH 50.14.00.35-03. The date of thesis defending 26.10.2011, “Nicoale Testemitanu” SUMP.

Brief information on the thesis:

Research goal: to study the posibilities of surgical techniques in the treatment of malformative urinary pathologies in newborns and babies under 3 years depending on the type of congenital abnormality to improve results of medical and surgical treatment.

Research objectives: evaluation of clinical, laboratory and urinary system morphology aspects; elaboration of the protocol of diagnosis, pharmacotherapy, surgery and prevention; postoperative evaluation of children with malformative urinary pathologies; assessment of efficiency of used diagnosis and treatment strategies in comparison with traditional ones.

The study novelty consists in concrete definition of the role of diagnostic, clinical, imagistic, laboratory and histological options in choosing the surgical strategy. By means of histological analysis malformative characteristics of the superior excretory system were determined and correlations between imaging manifestations and macroscopic structural architectonic and morphometric characteristics of pathologic processes were assessed. The assessment of biochemical blood markers allows to determine the intensity of the inflammatory process, the severity of alterations of cellular membranes and, as a result, to choose the differential treatment tactics.

Actually the specialty code is 321.14. Pediatric Surgery in conformity with Scientific Specialties Nomenclature. Approved by the Government Decision nr. 199 of 13 March 2013 (published in the Monitorul Oficial nr. 60-63 (4378-4381, page 32).

Doctoral thesis, author: Barsan Aliona, competitor, Scientific Advisor – Babuci Stanislav, MD, PhD, senior researcher.

The theme of thesis: “The optimization of surgical methods of correction of diaphragmatic-pleural hernias and diaphragmatic eventrations in children.”

Pediatric Surgery – 14.00.35. Specialized Scientific Consilium DH 50.14.00.35-03, The date of thesis defending 26.10.2011, “Nicoale Testemitanu” SUMP.

Brief information about thesis:

Research goal: to improve results of surgical treatment in children with congenital diaphragmatic hernias on the basis of the analysis of clinical and evolutional, morphological and functional characteristics of the disease, associated malformations and concomitant diseases.

Research objectives: to determine morphologic specific features of the hemidiaphragm and other vital organs that develop in children with diaphragmatic hernias and eventrations, to assess morphologic modifications of the placenta and its appendages  with the assessment of the role of feto-placental vascularization in the postnatal evolution of this malformation.

Scientific novelty: The role of clinical and laboratory modifications in the assessment of the severity of pulmonary hypoplasia and hypertension in diaphragmatic hernias and eventrations in children of different ages was assessed. Clinical efficiency of the preoperative and postoperative management, as well as of surgical methods in these patients was determined.

Theoretic importance: Feto-placental circulation disturbances alter significantly the postnatal condition of newborns with congenital diaphragmatic hernias due to chronic fetal hypoxia and acidemia. Local and systemic inflammatory processes determine the evolution and prognosis of this congenital malformation.

PhD thesis, author: Boian Gavril, senior researcher, Scientific adviser – Gudumac Eva, MD, PhD, professor, Academician of the Academy of Sciences of the Republic of Moldova, Honorary Citizen.

The theme of thesis: “Differential diagnosis and surgical, etiopathogenic, individualized treatment of chronic colostasis syndrome in children”., Specialized Scientific Consilium DH 50.14.00.35-06*, 04.07.2012.

The brief information on the thesis.

The research goal and objectives: to assess specific characteristics of clinical, laboratory, diagnostic, differential diagnostic and surgical etiopathogenic treatment in chronic colostasis syndrome in children; to determine risk factors; to assess informative value of clinical and laboratory methods of examination; to elaborate the algorithm of differential diagnosis and optimal surgical treatment on the basis of obtained results of the assessment of the efficiency of developed diagnostic and treatment program.

The scientific novelty: In this study the informative-diagnostic value of general and regional, clinical and laboratory methods of examination with the purpose to reveal chronic colostasis syndrome in children was assessed. The correlations of clinical and laboratory modifications in different anatomic and physiologic forms of the disease were studied. Imaging methods, neurophysiologic and histological examinations, differential diagnostic priority were demonstrated.

The scientific problem solved in the thesis: On the basis of this study clinical and laboratory specific features of chronic colostasis syndrome in children depending on age, causal factor, duration of the disease, complications and co-morbidities were ascertained. The algorithm of diagnostic and medico-surgical etiopathogenic individualized treatment, as well as the functional and social rehabilitation strategy of children operated for chronic colostasis syndrome  were elaborated.